Manual of Clinical Microbiology


Mechanisms of Resistance to Antiparasitic Agents

Last Updated:2023

Parasitic diseases rank among the most prevalent and severe diseases worldwide. While there are a number of tools used for control of parasitic diseases, such as diagnosis, surveillance, and active…


The development of resistance to all antimalarial drugs poses the greatest challenge for malaria control and prevention globally. The evolution of parasites resistant to antimalarial drugs is a common occurrence,…


Infection with Trichomonas vaginalis is one of the most common causes of human vaginitis as well as the second most prevalent sexually transmitted disease in the United States of America…


Leishmaniasis is transmitted to humans by phlebotomine sandfly vectors and manifests as a variety of syndromes. Depending on which of the over 20 species of Leishmania that infect humans is…


Praziquantel is the only drug currently being used for treatment of schistosomiasis. It is effective against all schistosome species that infect humans and makes up the backbone of schistosomiasis control…

Soil‐Transmitted Helminthiases

The widespread use of albendazole, mebendazole, levamisole, and pyrantel in PC programs to control soil‐transmitted helminth (STH; Ascaris lumbricoides, Trichuris trichiura, and the hookworms)…

Future Perspectives

Several factors contribute to the emergence of drug‐resistant parasites. Those parasite species with short life cycles and high multiplication rates that occur in areas of intense transmission are most likely…

Section Editor: Gary W. Procop

Volume Editor: Bobbi S. Pritt

Editors in Chief: Karen C. Carroll and Michael A. Pfaller

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